SRI 抗体 (AA 32-116)
Quick Overview for SRI 抗体 (AA 32-116) (ABIN7179479)
抗原
See all SRI 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-116
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交叉反应
- Staphylococcus aureus
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA)
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亚型
- IgG
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anti-Sorcin (SRI) (AA 1-198) antibody
SRI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Sorcin (SRI) (AA 1-198) antibodySRI 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) (AA 1-198) antibodySRI 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) antibodyKO Validated SRI 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) (AA 29-169) antibodySRI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) (C-Term) antibodySRI 适用: 人, 大鼠, 马, 犬, Cow, 绵羊, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) (AA 96-145) antibodySRI 适用: 人, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SRI (Sorcin (SRI))
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别名
- scn
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背景
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Background: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.
Aliases: scn antibody, SA1754 antibody, Staphylococcal complement inhibitor antibody, SCIN antibody
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UniProt
- Q99SU9
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途径
- Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
抗原
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