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IL12B 抗体 (AA 23-327)

This anti-IL12B antibody is a 兔 多克隆 antibody detecting IL12B in WB, ELISA 和 IHC. Suitable for 绵羊.
产品编号 ABIN7179323
发货至: 中国

Quick Overview for IL12B 抗体 (AA 23-327) (ABIN7179323)

抗原

See all IL12B 抗体
IL12B (Interleukin 12 beta (IL12B))

适用

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绵羊

宿主

  • 99
  • 41
  • 3
  • 2

克隆类型

  • 98
  • 47
多克隆

标记

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This IL12B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 23-327

    交叉反应

    绵羊

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Sheep Interleukin-12 subunit beta protein (23-327AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    IL12B (Interleukin 12 beta (IL12B))

    别名

    IL12B

    背景

    Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC By similarity.Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis By similarity.

    Aliases: IL12B antibody, Interleukin-12 subunit beta antibody, IL-12B antibody, Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody, CLMF p40 antibody, IL-12 subunit p40 antibody

    UniProt

    P68220

    途径

    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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