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PRNP 抗体 (AA 29-231) (FITC)

The FITC-conjugated 兔 多克隆 anti-PRNP antibody (ABIN7178935) specifically detects PRNP. The antibody is reactive with 大鼠 samples.
产品编号 ABIN7178935
发货至: 中国
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Quick Overview for PRNP 抗体 (AA 29-231) (FITC) (ABIN7178935)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This PRNP antibody is conjugated to FITC

应用范围

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  • 抗原表位

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    AA 29-231

    原理

    Prnp Antibody, FITC conjugated

    交叉反应

    大鼠

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Rat Major prion protein (29-231AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    Prnp

    背景

    Background: Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.

    Aliases: Prnp antibody, Prn antibody, Prp antibody, Major prion protein antibody, PrP antibody, CD antigen CD230 antibody

    UniProt

    P13852

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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