Hepcidin 抗体
Quick Overview for Hepcidin 抗体 (ABIN7178664)
抗原
See all Hepcidin (HAMP) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of Human HAMP
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亚型
- IgG
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应用备注
- WB:1:500-1:2000, IHC:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Store at -20 °C or -80 °C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
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别名
- HAMP
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背景
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Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.
Aliases: Hamp antibody, HEPC antibody, HEPC_HUMAN antibody, Hepc20 antibody, Hepc25 antibody, HEPCIDIN antibody, Hepcidin 20 antibody, Hepcidin 25 antibody, Hepcidin antimicrobial peptide antibody, Hepcidin-20 antibody, Hepcidin25 antibody, HFE2 antibody, HFE2B antibody, LEAP 1 antibody, LEAP-1 antibody, LEAP1 antibody, Liver expressed antimicrobial peptide antibody, Liver-expressed antimicrobial peptide 1 antibody, PLTR antibody, Putative liver tumor regressor antibody
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UniProt
- P81172
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途径
- Hormone Activity, Transition Metal Ion Homeostasis
抗原
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