Glutamate Receptor 3 抗体
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北京 101111
Quick Overview for Glutamate Receptor 3 抗体 (ABIN7178663)
抗原
See all Glutamate Receptor 3 (GRIA3) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GRIA3 Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of Human GRIA3
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) antibody
GRIA3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (AA 451-550) antibodyGRIA3 适用: 人, 大鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (AA 649-823) antibodyGRIA3 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (AA 200-490) antibodyGRIA3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (AA 151-250) antibodyGRIA3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) antibodyGRIA3 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) antibodyGRIA3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (N-Term) antibodyGRIA3 适用: 人, 大鼠 WB, IHC, IF, ICC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (AA 60-73), (Extracellular) antibodyGRIA3 适用: 大鼠 WB, IHC, IF, IP, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) (AA 151-250) antibodyGRIA3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
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别名
- GRIA3
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背景
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Background: AMPA- (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainite- and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Post-transcriptional modifications (alternative splicing and nuclear RNA editing) and post-translational modifications (glycosylation, phoshorylation) result in a very large number of permutations, fine-tuning the kinetic properties of AMPARs. GluR 3 knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission. Aberrant GluR 3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Retts syndrome, amyotrophic lateral sclerosis and Alzheimer disease.
Aliases: AMPA 3 antibody, AMPA selective glutamate receptor 3 antibody, AMPA-selective glutamate receptor 3 antibody, dJ1171F9.1 antibody, GluA3 antibody, GLUK3 antibody, GluR 3 antibody, GLUR C antibody, GLUR K3 antibody, GluR-3 antibody, GluR-C antibody, GluR-K3 antibody, GLUR3 antibody, GLURC antibody, Glutamate ionotropic receptor AMPA type subunit 3 antibody, Glutamate receptor 3 antibody, Glutamate receptor C antibody, Glutamate receptor ionotrophic AMPA 3 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor subunit 3 antibody, Glutamate receptor, ionotropic, AMPA 3 antibody, GRIA 3 antibody, Gria3 antibody, GRIA3_HUMAN antibody, Ionotrophic Glutamate Receptor antibody, MRX94 antibody
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UniProt
- P42263
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途径
- PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane
抗原
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