CD8 alpha 抗体 (PE)
Quick Overview for CD8 alpha 抗体 (PE) (ABIN7178438)
抗原
See all CD8 alpha (CD8A) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Affinity purified
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免疫原
- Recombinant Protein
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亚型
- IgG1, IgG1 kappa
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应用备注
- Recommended dilution:IF:1:100-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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别名
- CD8A
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背景
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Background: COV8 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development.* Ratio of CD4 and CD8 is important for monitor of HIV infection.1. Engleman EG et al. (1981) J Exp Med 153: 193-198.2. Haynes, B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Parnes, JR. et al. (1989). Adv. Immunol. 44,256-311.4. Bikah G. et al. (1996). Science 274:1906.
Aliases: N/A
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UniProt
- P01732
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途径
- TCR Signaling
抗原
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