Cobra Venom Factor,CVF (AA 733-984) 抗体 (HRP)
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- 抗原
- Cobra Venom Factor,CVF
- 抗原表位
- AA 733-984
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适用
- Cobra
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- HRP
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应用范围
- ELISA
- 交叉反应
- Cobra
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Naja kaouthia Cobra venom factor protein (733-984AA)
- 亚型
- IgG
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anti-Cobra Venom Factor,CVF (AA 733-984) antibody
适用: Cobra ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Cobra Venom Factor,CVF
- 别名
- Cobra venom factor
- 背景
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Background: Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
Aliases: antibody, Cobra venom factor antibody, CVF antibody, CVFk antibody, Complement C3 homolog) [Cleaved into: Cobra venom factor alpha chain, Cobra venom factor gamma chain, Cobra venom factor beta chain] antibody
- UniProt
- Q91132
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