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TXNIP 抗体 (AA 1-397) (HRP)

This anti-TXNIP antibody is a 兔 多克隆 antibody detecting TXNIP in ELISA. Suitable for 小鼠.
产品编号 ABIN7177898
发货至: 中国

Quick Overview for TXNIP 抗体 (AA 1-397) (HRP) (ABIN7177898)

抗原

See all TXNIP 抗体
TXNIP (Thioredoxin Interacting Protein (TXNIP))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This TXNIP antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 1-397

    交叉反应

    小鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Mouse Thioredoxin-interacting protein (1-397AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TXNIP (Thioredoxin Interacting Protein (TXNIP))

    别名

    Txnip

    背景

    Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.

    Aliases: Txnip antibody, Vdup1 antibody, Thioredoxin-interacting protein antibody, Vitamin D3 up-regulated protein 1 antibody

    UniProt

    Q8BG60

    途径

    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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