IRF8 抗体 (AA 1-424) (HRP)
Quick Overview for IRF8 抗体 (AA 1-424) (HRP) (ABIN7177348)
抗原
See all IRF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-424
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交叉反应
- 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Mouse Interferon regulatory factor 8 protein (1-424AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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别名
- Irf8
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背景
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Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\'-TGAnTCA/GAAA-3\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
Aliases: Irf8 antibody, Icsbp antibody, Icsbp1 antibody, Interferon regulatory factor 8 antibody, IRF-8 antibody, Interferon consensus sequence-binding protein antibody, ICSBP antibody
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UniProt
- P23611
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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