FAIM3 抗体 (AA 18-262) (HRP)
Quick Overview for FAIM3 抗体 (AA 18-262) (HRP) (ABIN7177188)
抗原
See all FAIM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-262
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交叉反应
- 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
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别名
- Fcmr
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背景
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Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Aliases: Fcmr antibody, Faim3 antibody, TosoFas apoptotic inhibitory molecule 3 antibody, IgM Fc fragment receptor antibody, Regulator of Fas-induced apoptosis Toso antibody
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UniProt
- A1KXC4
抗原
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