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MMP13 抗体 (AA 105-472)

This anti-MMP13 antibody is a 兔 多克隆 antibody detecting MMP13 in IHC 和 ELISA. Suitable for 小鼠.
产品编号 ABIN7177113
发货至: 中国

Quick Overview for MMP13 抗体 (AA 105-472) (ABIN7177113)

抗原

See all MMP13 抗体
MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This MMP13 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 105-472

    交叉反应

    小鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Mouse Collagenase 3 protein (105-472AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:200-1:500,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

    别名

    Mmp13

    背景

    Background: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.

    Aliases: Mmp13 antibody, Collagenase 3 antibody, EC 3.4.24.- antibody, Matrix metalloproteinase-13 antibody, MMP-13 antibody

    UniProt

    P33435
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