Gag (AA 216-478) 抗体 (FITC)
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- 抗原
- Gag
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抗原表位
- AA 216-478
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适用
- Moloney Murine Leukemia Virus (MoMuLV)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- FITC
- 应用范围
- 请咨询
- 交叉反应
- Moloney Murine Leukemia Virus (MoMuLV)
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA)
- 亚型
- IgG
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Gag
- 物质类
- Viral Protein
- 背景
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Background: Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.Matrix protein p15 targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex.Capsid protein p30 forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.Nucleocapsid protein p10 is involved in the packaging and encapsidation of two copies of the genome. Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5\\\'-end of the genome. This binding is dependent on genome dimerization.
Aliases: gag antibody, Gag polyprotein antibody, Pr65gag antibody, Core polyprotein) [Cleaved into: Matrix protein p15 antibody, MA), RNA-binding phosphoprotein p12 antibody, pp12), Capsid protein p30 antibody, CA), Nucleocapsid protein p10-Gag antibody, NC-gag)] antibody
- UniProt
- P03332
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