GLIS2 抗体 (AA 332-505)
Quick Overview for GLIS2 抗体 (AA 332-505) (ABIN7176582)
抗原
See all GLIS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 332-505
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Zinc finger protein GLIS2 protein (332-505AA)
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亚型
- IgG
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anti-GLIS Family Zinc Finger 2 (GLIS2) (N-Term) antibody
GLIS2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 2 (GLIS2) (AA 83-132) antibodyGLIS2 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 2 (GLIS2) (AA 183-232) antibodyGLIS2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
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别名
- GLIS2
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背景
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Background: Can act either as a transcriptional repressor or as a transcriptional activator, depending on the cell context. Acts as a repressor of the Hedgehog signaling pathway (By similarity). Represses the Hedgehog-dependent expression of Wnt4 (By similarity). Necessary to maintain the differentiated epithelial phenotype in renal cells through the inhibition of SNAI1, which itself induces the epithelial-to-mesenchymal transition (By similarity). Represses transcriptional activation mediated by CTNNB1 in the Wnt signaling pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation (By similarity).
Aliases: FLJ38247 antibody, GLI similar 2 antibody, GLI-similar 2 antibody, GLIS 2 antibody, GLIS family zinc finger 2 antibody, glis2 antibody, GLIS2_HUMAN antibody, Kruppel like zinc finger protein GLIS2 antibody, Neuronal Krueppel-like protein antibody, Zinc finger protein GLIS2 antibody
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UniProt
- Q9BZE0
抗原
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