p107 抗体 (pSer975)
Quick Overview for p107 抗体 (pSer975) (ABIN713381)
抗原
See all p107 (RBL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer975
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human RBL1 around the phosphorylation site of Ser975
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亚型
- IgG
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anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 905-1014) antibody
RBL1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1007-1035), (C-Term) antibodyRBL1 适用: 人 WB 宿主: 兔 Polyclonal RB40387 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1-1014) antibodyRBL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (C-Term) antibodyRBL1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7537 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 201-500) antibodyRBL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 143-192) antibodyRBL1 适用: 人, 小鼠, Cow, 马, Pig, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 935-984) antibodyRBL1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 100-200) antibodyRBL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (N-Term) antibodyRBL1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
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别名
- p107
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背景
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Synonyms: PRB1, p107, CP107, Retinoblastoma-like protein 1, 107 kDa retinoblastoma-associated protein, RBL1
Background: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
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基因ID
- 5933
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UniProt
- P28749
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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