WT1 抗体 (AA 1-449)
Quick Overview for WT1 抗体 (AA 1-449) (ABIN7175818)
抗原
See all WT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-449
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Wilms tumor protein (1-449AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- WT1 (Wilms Tumor 1 (WT1))
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别名
- WT1
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背景
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Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5\'-CGCCCCCGC-3\'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Aliases: WIT 2 antibody, WT 1 antibody, AWT1 antibody, FWT1 antibody, GUD antibody, NPHS4 antibody, WAGR antibody, Wilms tumor 1 antibody, Wilms Tumor antibody, Wilms tumor protein antibody, Wilms' tumor gene antibody, Wilms' tumor protein antibody, WIT2 antibody, WT antibody, WT1 antibody, WT1_HUMAN antibody, WT33 antibody
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UniProt
- P19544
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途径
- Tube Formation
抗原
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