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WDR41 抗体 (AA 7-284) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-WDR41 antibody specifically detects WDR41 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7175752
发货至: 中国
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Quick Overview for WDR41 抗体 (AA 7-284) (Biotin) (ABIN7175752)

抗原

WDR41 (WD Repeat Domain 41 (WDR41))

适用

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宿主

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克隆类型

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多克隆

标记

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This WDR41 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 7-284

    原理

    WDR41 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human WD repeat-containing protein 41 protein (7-284AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    WDR41 (WD Repeat Domain 41 (WDR41))

    别名

    WDR41

    背景

    Background: Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27193190, PubMed:27103069, PubMed:27617292, PubMed:28195531). The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (PubMed:27103069). The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity (PubMed:27103069, PubMed:27617292).

    Aliases: FLJ10904 antibody, MSTP048 antibody, WD repeat domain 41 antibody, WD repeat protein 41 antibody, WD repeat-containing protein 41 antibody, WDR 41 antibody, WDR41 antibody, WDR41_HUMAN antibody

    UniProt

    Q9HAD4
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