MORG1 抗体 (AA 64-315) (HRP)
Quick Overview for MORG1 抗体 (AA 64-315) (HRP) (ABIN7175713)
抗原
See all MORG1 (wdr83) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 64-315
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human WD repeat domain-containing protein 83 protein (64-315AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
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别名
- WDR83
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背景
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Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.
Aliases: MAPK organizer 1 antibody, MGC4238 antibody, Mitogen activated protein kinase organizer 1 antibody, Mitogen-activated protein kinase organizer 1 antibody, MORG 1 antibody, WD repeat domain-containing protein 83 antibody, wdr83 antibody, WDR83_HUMAN antibody
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UniProt
- Q9BRX9
抗原
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