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WIPI1 抗体 (AA 187-446)

This anti-WIPI1 antibody is a 兔 多克隆 antibody detecting WIPI1 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7175707
发货至: 中国

Quick Overview for WIPI1 抗体 (AA 187-446) (ABIN7175707)

抗原

See all WIPI1 抗体
WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

适用

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宿主

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克隆类型

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多克隆

标记

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This WIPI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 187-446

    交叉反应

    人, 小鼠

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human WD repeat domain phosphoinositide-interacting protein 1 protein (187-446AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

    别名

    WIPI1

    背景

    Background: Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation-induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway.

    Aliases: ATG 18 antibody, ATG18 antibody, Atg18 protein homolog antibody, ATG18A antibody, FLJ10055 antibody, WD repeat domain phosphoinositide interacting 1 antibody, WD repeat domain phosphoinositide interacting protein 1 antibody, WD repeat domain phosphoinositide-interacting protein 1 antibody, WD40 repeat protein interacting with phosphoinositides of 49 kDa antibody, WD40 repeat protein interacting with phosphoInositides of 49 kDa antibody, WIPI 1 alpha antibody, WIPI 1 antibody, WIPI 49 antibody, WIPI 49 kDa antibody, WIPI-1 antibody, wipi1 antibody, WIPI1_HUMAN antibody, WIPI49 antibody

    UniProt

    Q5MNZ9

    途径

    Nuclear Hormone Receptor Binding, ER-Nucleus Signaling
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