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WDFY3 抗体 (AA 1-100) (Biotin)

This anti-WDFY3 antibody is a 兔 多克隆 antibody detecting WDFY3 in ELISA. Suitable for 人.
产品编号 ABIN7175700
发货至: 中国

Quick Overview for WDFY3 抗体 (AA 1-100) (Biotin) (ABIN7175700)

抗原

See all WDFY3 抗体
WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

适用

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宿主

  • 35
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克隆类型

  • 36
  • 3
多克隆

标记

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This WDFY3 antibody is conjugated to Biotin

应用范围

  • 13
  • 10
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ELISA
  • 抗原表位

    • 4
    • 3
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    • 1
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    AA 1-100

    原理

    WDFY3 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human WD repeat and FYVE domain-containing protein 3 protein (1-100AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

    别名

    WDFY3

    背景

    Background: Required for selective autophagy (aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.

    Aliases: WDFY3 antibody, KIAA0993 antibody, WD repeat and FYVE domain-containing protein 3 antibody, Autophagy-linked FYVE protein antibody, Alfy antibody

    UniProt

    Q8IZQ1
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