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SNF8 抗体 (AA 1-258)

This anti-SNF8 antibody is a 兔 多克隆 antibody detecting SNF8 in ELISA 和 IF. Suitable for 人.
产品编号 ABIN7175340
发货至: 中国

Quick Overview for SNF8 抗体 (AA 1-258) (ABIN7175340)

抗原

See all SNF8 抗体
SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

适用

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宿主

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克隆类型

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多克隆

标记

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This SNF8 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 1-258

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Vacuolar-sorting protein SNF8 protein (1-258AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

    别名

    SNF8

    背景

    Background: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

    Aliases: Dot3 antibody, ELL associated protein of 30 kDa antibody, ELL-associated protein of 30 kDa antibody, ESCRT-II complex subunit VPS22 antibody, hVps22 antibody, snf8 antibody, SNF8 ESCRTII complex subunit homolog (S cerevisiae) antibody, SNF8_HUMAN antibody, Vacuolar sorting protein SNF8 antibody, Vacuolar-sorting protein SNF8 antibody, VPS22 antibody

    UniProt

    Q96H20
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