VPS52 抗体 (AA 277-377)
Quick Overview for VPS52 抗体 (AA 277-377) (ABIN7175328)
抗原
See all VPS52 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 277-377
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Vacuolar protein sorting-associated protein 52 homolog protein (277-377AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))
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别名
- VPS52
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背景
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Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).
Aliases: VPS52 antibody, SACM2LVacuolar protein sorting-associated protein 52 homolog antibody, SAC2 suppressor of actin mutations 2-like protein antibody
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UniProt
- Q8N1B4
抗原
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