VPS18 抗体 (AA 298-515)
Quick Overview for VPS18 抗体 (AA 298-515) (ABIN7175284)
抗原
See all VPS18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 298-515
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Vacuolar protein sorting-associated protein 18 homolog protein (298-515AA)
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亚型
- IgG
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anti-Vacuolar Protein Sorting 18 Homolog (VPS18) (AA 3-100) antibody
VPS18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2G10 unconjugated
anti-Vacuolar Protein Sorting 18 Homolog (VPS18) (AA 701-800) antibodyVPS18 适用: 人 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 18 Homolog (VPS18) (AA 3-100) antibodyVPS18 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 4E9 unconjugated
anti-Vacuolar Protein Sorting 18 Homolog (VPS18) (AA 3-100) antibodyVPS18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2G10 unconjugated
anti-Vacuolar Protein Sorting 18 Homolog (VPS18) antibodyVPS18 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Vacuolar Protein Sorting 18 Homolog (VPS18) (AA 1-580) antibodyVPS18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- VPS18 (Vacuolar Protein Sorting 18 Homolog (VPS18))
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别名
- VPS18
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背景
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Background: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:25783203). Involved in dendrite development of Pukinje cells (By similarity).
Aliases: hVPS18 antibody, PEP3 antibody, Vacuolar protein sorting 18 antibody, Vacuolar protein sorting protein 18 antibody, Vacuolar protein sorting-associated protein 18 homolog antibody, vps18 antibody, VPS18_HUMAN antibody
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UniProt
- Q9P253
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途径
- Asymmetric Protein Localization
抗原
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