UVRAG 抗体 (AA 375-425)
Quick Overview for UVRAG 抗体 (AA 375-425) (ABIN7175178)
抗原
See all UVRAG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 375-425
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human UV radiation resistance-associated gene protein (375-425AA)
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亚型
- IgG
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anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 501-699) antibody
UVRAG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 601-699) antibodyUVRAG 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E8 unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (Biotin)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (PE)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (Atto 594)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 594
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (Atto 488)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (Atto 390)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-UV Radiation Resistance Associated Gene (UVRAG) antibodyUVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (HRP)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (FITC)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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别名
- UVRAG
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背景
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Background: Versatile protein that is involved in regulation of differenent cellular pathways implicated in membrane trafficking. Involved in regulation of the COPI-dependent retrograde transport from Golgi and the endoplasmic reticulum by associating with the NRZ complex, the function is dependent on its binding to phosphatidylinositol 3-phosphate (PtdIns(3)P) (PubMed:24056303). During autophagy acts as regulatory subunit of the alternative PI3K complex II (PI3KC3-C2) that mediates formation of phosphatidylinositol 3-phosphate and is believed to be involved in maturation of autophagosomes and endocytosis. Activates lipid kinase activity of PIK3C3. Involved in the regulation of degradative endocytic trafficking and cytokinesis, and in regulation of ATG9A transport from the Golgi to the autophagosome, the functions seems to implicate its association with PI3KC3-C2 (PubMed:16799551, PubMed:20643123, PubMed:24056303). Involved in maturation of autophagosomes and degradative endocytic trafficking independently of BECN1 but depending on its association with a class C Vps complex (possibly the HOPS complex), the association is also proposed to promote autophagosome recruitment and activation of Rab7 and endosome-endosome fusion events (PubMed:18552835). Enhances class C Vps complex (possibly HOPS complex) association with a SNARE complex and promotes fusogenic SNARE complex formation during late endocytic membrane fusion (PubMed:24550300). In case of negative-strand RNA virus infection is required for efficient virus entry, promotes endocytic transport of virions and is implicated in a VAMP8-specific fusogenic SNARE complex assembly (PubMed:24550300).
Aliases: Beclin 1 binding protein antibody, DHTX antibody, Disrupted in heterotaxy antibody, p63 antibody, UV radiation resistance associated antibody, UV radiation resistance associated gene antibody, UV radiation resistance associated gene protein antibody, UV radiation resistance-associated gene protein antibody, UVRAG antibody, UVRAG_HUMAN antibody, VPS38 antibody
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UniProt
- Q9P2Y5
抗原
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