Myosin XVIIIA 抗体 (AA 1849-2054)
Quick Overview for Myosin XVIIIA 抗体 (AA 1849-2054) (ABIN7174981)
抗原
See all Myosin XVIIIA (MYO18A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1849-2054
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Unconventional myosin-XVIIIa protein (1849-2054AA)
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亚型
- IgG
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anti-Myosin XVIIIA (MYO18A) (Internal Region) antibody
MYO18A 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin XVIIIA (MYO18A) (AA 1970-2054) antibodyMYO18A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Myosin XVIIIA (MYO18A)
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别名
- MYO18A
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背景
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Background: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939).
Aliases: MYO18A antibody, CD245 antibody, KIAA0216 antibody, MYSPDZ antibody, Unconventional myosin-XVIIIa antibody, Molecule associated with JAK3 N-terminus antibody, MAJN antibody, Myosin containing a PDZ domain antibody, Surfactant protein receptor SP-R210 antibody, SP-R210 antibody
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UniProt
- Q92614
抗原
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