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UBA1 抗体 (AA 730-881) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-UBA1 antibody specifically detects UBA1 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7174521
发货至: 中国
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Quick Overview for UBA1 抗体 (AA 730-881) (Biotin) (ABIN7174521)

抗原

See all UBA1 抗体
UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

适用

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宿主

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克隆类型

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多克隆

标记

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This UBA1 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 730-881

    原理

    UBA1 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Ubiquitin-like modifier-activating enzyme 1 protein (730-881AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

    别名

    UBA1

    背景

    Background: Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system (PubMed:1606621, PubMed:1447181). Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (PubMed:1447181). Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (PubMed:22456334).

    Aliases: A1S9 antibody, A1S9 protein antibody, A1S9T and BN75 temperature sensitivity complementing antibody, A1S9T antibody, A1ST antibody, AMCX1 antibody, CFAP124 antibody, CTD-2522E6.1 antibody, GXP 1 antibody, GXP1 antibody, MGC4781 antibody, POC20 antibody, POC20 centriolar protein homolog antibody, Protein A1S9 antibody, SMAX2 antibody, Uba1 antibody, UBA1, ubiquitin-activating enzyme E1 homolog A antibody, UBA1_HUMAN antibody, UBA1A antibody, UBE 1 antibody, UBE 1X antibody, UBE1 antibody, UBE1X antibody, Ubiquitin activating enzyme E1 antibody, Ubiquitin-activating enzyme E1 antibody, Ubiquitin-like modifier-activating enzyme 1 antibody

    UniProt

    P22314
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