UBA1 抗体 (AA 730-881)
Quick Overview for UBA1 抗体 (AA 730-881) (ABIN7174520)
抗原
See all UBA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 730-881
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ubiquitin-like modifier-activating enzyme 1 protein (730-881AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))
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别名
- UBA1
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背景
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Background: Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system (PubMed:1606621, PubMed:1447181). Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (PubMed:1447181). Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (PubMed:22456334).
Aliases: A1S9 antibody, A1S9 protein antibody, A1S9T and BN75 temperature sensitivity complementing antibody, A1S9T antibody, A1ST antibody, AMCX1 antibody, CFAP124 antibody, CTD-2522E6.1 antibody, GXP 1 antibody, GXP1 antibody, MGC4781 antibody, POC20 antibody, POC20 centriolar protein homolog antibody, Protein A1S9 antibody, SMAX2 antibody, Uba1 antibody, UBA1, ubiquitin-activating enzyme E1 homolog A antibody, UBA1_HUMAN antibody, UBA1A antibody, UBE 1 antibody, UBE 1X antibody, UBE1 antibody, UBE1X antibody, Ubiquitin activating enzyme E1 antibody, Ubiquitin-activating enzyme E1 antibody, Ubiquitin-like modifier-activating enzyme 1 antibody
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UniProt
- P22314
抗原
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