UBE2W 抗体 (AA 1-151) (FITC)
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北京 101111
Quick Overview for UBE2W 抗体 (AA 1-151) (FITC) (ABIN7174504)
抗原
See all UBE2W 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-151
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原理
- UBE2W Antibody, FITC conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Ubiquitin-conjugating enzyme E2 W protein (1-151AA)
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亚型
- IgG
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anti-Ubiquitin-Conjugating Enzyme E2W (UBE2W) (AA 17-112) antibody
UBE2W 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 7G4 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2W (UBE2W) (AA 105-133), (C-Term) antibodyUBE2W 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32985 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2W (UBE2W) (AA 71-151) antibodyUBE2W 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2W (UBE2W) (AA 40-110) antibodyUBE2W 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2W (UBE2W) (AA 17-112) antibodyUBE2W 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))
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别名
- UBE2W
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背景
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Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length of ubiquitin chain attached to STUB1/CHIP substrates by ATXN3. After UV irradiation, but not after mitomycin-C (MMC) treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. In vitro catalyzes \'Lys-11\'-linked polyubiquitination. Transfers ubiquitin in complex with RING/U-box type E3s that do not have active site cysteine residues to form thioester bonds with ubiquitin, and preferentially ubiquitinates the N-terminus of substrates, such as ATXN3, STUB1 and SUMO2.
Aliases: FLJ11011 antibody, hUBC 16 antibody, hUBC16 antibody, Probable ubiquitin conjugating enzyme E2 W antibody, Probable ubiquitin-conjugating enzyme E2 W antibody, UBC 16 antibody, UBC-16 antibody, UBC16 antibody, UBE 2W antibody, ube2w antibody, UBE2W_HUMAN antibody, Ubiquitin carrier protein W antibody, Ubiquitin conjugating enzyme 16 antibody, Ubiquitin conjugating enzyme E2 W antibody, Ubiquitin conjugating enzyme E2W antibody, Ubiquitin protein ligase W antibody, Ubiquitin-protein ligase W antibody
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UniProt
- Q96B02
抗原
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