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UBE2W 抗体 (AA 1-151)

UBE2W 适用: 人 ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7174502
发货至: 中国
  • 抗原 See all UBE2W 抗体
    UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 1-151
    适用
    • 30
    • 24
    • 23
    宿主
    • 42
    • 3
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2W antibody is un-conjugated
    应用范围
    • 23
    • 20
    • 13
    • 13
    • 13
    • 5
    • 3
    • 2
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Ubiquitin-conjugating enzyme E2 W protein (1-151AA)
    亚型
    IgG
    Top Product
    Discover our top product UBE2W Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))
    别名
    UBE2W (UBE2W 产品)
    别名
    UBE2W antibody, im:6905459 antibody, si:ch211-193n21.4 antibody, ube2wa antibody, UBC-16 antibody, UBC16 antibody, 6130401J04Rik antibody, ubiquitin conjugating enzyme E2 W antibody, ubiquitin-conjugating enzyme E2W (putative) antibody, ubiquitin conjugating enzyme E2 W (putative) antibody, ubiquitin conjugating enzyme E2W (putative) antibody, ubiquitin-conjugating enzyme E2W antibody, UBE2W antibody, ube2w antibody, Ube2w antibody
    背景

    Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length of ubiquitin chain attached to STUB1/CHIP substrates by ATXN3. After UV irradiation, but not after mitomycin-C (MMC) treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. In vitro catalyzes \'Lys-11\'-linked polyubiquitination. Transfers ubiquitin in complex with RING/U-box type E3s that do not have active site cysteine residues to form thioester bonds with ubiquitin, and preferentially ubiquitinates the N-terminus of substrates, such as ATXN3, STUB1 and SUMO2.

    Aliases: FLJ11011 antibody, hUBC 16 antibody, hUBC16 antibody, Probable ubiquitin conjugating enzyme E2 W antibody, Probable ubiquitin-conjugating enzyme E2 W antibody, UBC 16 antibody, UBC-16 antibody, UBC16 antibody, UBE 2W antibody, ube2w antibody, UBE2W_HUMAN antibody, Ubiquitin carrier protein W antibody, Ubiquitin conjugating enzyme 16 antibody, Ubiquitin conjugating enzyme E2 W antibody, Ubiquitin conjugating enzyme E2W antibody, Ubiquitin protein ligase W antibody, Ubiquitin-protein ligase W antibody

    UniProt
    Q96B02
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