UBE2V1 抗体 (AA 2-147)
Our Local Distributor
北京 101111
Quick Overview for UBE2V1 抗体 (AA 2-147) (ABIN7174489)
抗原
See all UBE2V1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2-147
-
原理
- UBE2V1 Antibody
-
纯化方法
- Protein G purified
-
纯度
- >95 %
-
免疫原
- Recombinant Human Ubiquitin-conjugating enzyme E2 variant 1 protein (2-147AA)
-
亚型
- IgG
-
-
anti-Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (AA 1-147) antibody
UBE2V1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (AA 1-147) antibodyUBE2V1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) antibodyUBE2V1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (AA 1-103) antibodyUBE2V1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (AA 113-145) antibodyUBE2V1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (C-Term) antibodyUBE2V1 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 马, Pig, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (AA 113-145), (C-Term) antibodyUBE2V1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB4387 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) antibodyUBE2V1 适用: 人, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
-
别名
- UBE2V1
-
背景
-
Background: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate \'Lys-63\'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes.
Aliases: CIR1 antibody, CROC-1 antibody, CROC1 antibody, CROC1A antibody, TRAF6-regulated IKK activator 1 beta Uev1A antibody, UB2V1_HUMAN antibody, UBE2V 1 antibody, UBE2V antibody, UBE2V1 antibody, Ubiquitin conjugating enzyme E2 variant 1 antibody, Ubiquitin-conjugating enzyme E2 variant 1 antibody, UEV-1 antibody, UEV1 antibody
-
UniProt
- Q13404
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
-
