Ube2t 抗体 (AA 1-197) (HRP)
Quick Overview for Ube2t 抗体 (AA 1-197) (HRP) (ABIN7174488)
抗原
See all Ube2t 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-197
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ubiquitin-conjugating enzyme E2 T protein (1-197AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
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别名
- UBE2T
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背景
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Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer \'Lys-11\'-, \'Lys-27\'-, \'Lys-48\'- and \'Lys-63\'-linked polyubiquitination.
Aliases: Cell proliferation inducing gene 50 protein antibody, Cell proliferation-inducing gene 50 protein antibody, HSPC150 antibody, HSPC150 protein similar to ubiquitin conjugating enzyme antibody, PIG50 antibody, Ube2t antibody, UBE2T_HUMAN antibody, Ubiquitin carrier protein T antibody, Ubiquitin conjugating enzyme antibody, ubiquitin conjugating enzyme E2 T antibody, Ubiquitin conjugating enzyme E2T antibody, Ubiquitin protein ligase T antibody, Ubiquitin-conjugating enzyme E2 T antibody, Ubiquitin-protein ligase T antibody
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UniProt
- Q9NPD8
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途径
- Chromatin Binding
抗原
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