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UBE2K 抗体 (AA 2-200)

This anti-UBE2K antibody is a 兔 多克隆 antibody detecting UBE2K in ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7174460
发货至: 中国

Quick Overview for UBE2K 抗体 (AA 2-200) (ABIN7174460)

抗原

See all UBE2K 抗体
UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

适用

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宿主

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克隆类型

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多克隆

标记

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This UBE2K antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 2-200

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Ubiquitin-conjugating enzyme E2 K protein (2-200AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:10-1:100, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

    别名

    UBE2K

    背景

    Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of \\\'Lys-48\\\'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B, in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1.

    Aliases: E2 25K antibody, E2(25K) antibody, HIP-2 antibody, Huntingtin interacting protein 2 antibody, Huntingtin-interacting protein 2 antibody, HYPG antibody, LIG antibody, UBC1 antibody, UBE2K antibody, UBE2K_HUMAN antibody, Ubiquitin carrier protein antibody, Ubiquitin conjugating enzyme E2 25 kDa antibody, ubiquitin conjugating enzyme E2K antibody, ubiquitin conjugating enzyme E2K (UBC1 homolog, yeast) antibody, Ubiquitin protein ligase antibody, Ubiquitin-conjugating enzyme E2 K antibody, Ubiquitin-conjugating enzyme E2(25K) antibody, Ubiquitin-conjugating enzyme E2-25 kDa antibody, Ubiquitin-conjugating enzyme E2-25K antibody, Ubiquitin-protein ligase antibody

    UniProt

    P61086
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