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Usp30 抗体 (AA 101-400)

This anti-Usp30 antibody is a 兔 多克隆 antibody detecting Usp30 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7174308
发货至: 中国

Quick Overview for Usp30 抗体 (AA 101-400) (ABIN7174308)

抗原

See all Usp30 抗体
Usp30 (Ubiquitin Specific Peptidase 30 (Usp30))

适用

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宿主

  • 32

克隆类型

  • 32
多克隆

标记

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This Usp30 antibody is un-conjugated

应用范围

  • 21
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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 9
    • 8
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    • 1
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    AA 101-400

    原理

    USP30 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 30 protein (101-400AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Usp30 (Ubiquitin Specific Peptidase 30 (Usp30))

    别名

    USP30

    背景

    Background: Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PARK2): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin\\\'s ability to drive mitophagy (PubMed:18287522, PubMed:24896179, PubMed:25527291, PubMed:25621951). Preferentially cleaves \\\'Lys-6\\\'- and \\\'Lys-11\\\'-linked polyubiquitin chains, 2 types of linkage that participate to mitophagic signaling (PubMed:25621951). Does not cleave efficiently polyubiquitin phosphorylated at \\\'Ser-65\\\' (PubMed:25527291). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (By similarity).

    Aliases: Deubiquitinating enzyme 30 antibody, FLJ40511 antibody, Ub-specific protease 30 antibody, Ubiquitin carboxyl terminal hydrolase 30 antibody, Ubiquitin carboxyl-terminal hydrolase 30 antibody, Ubiquitin specific peptidase 30 antibody, Ubiquitin specific processing protease 30 antibody, Ubiquitin thioesterase 30 antibody, Ubiquitin thiolesterase 30 antibody, Ubiquitin-specific-processing protease 30 antibody, UBP30_HUMAN antibody, usp30 antibody

    UniProt

    Q70CQ3
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