电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

USP3 抗体 (C-Term)

This anti-USP3 antibody is a 兔 多克隆 antibody detecting USP3 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7174308
发货至: 中国

Quick Overview for USP3 抗体 (C-Term) (ABIN7174308)

抗原

See all USP3 抗体
USP3 (Ubiquitin Specific Peptidase 3 (USP3))

适用

  • 71
  • 8
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 68
  • 3

克隆类型

  • 70
  • 1
多克隆

标记

  • 33
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This USP3 antibody is un-conjugated

应用范围

  • 56
  • 27
  • 21
  • 14
  • 13
  • 12
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-400, C-Term

    交叉反应

    人, 小鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 30 protein (101-400AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    USP3 (Ubiquitin Specific Peptidase 3 (USP3))

    别名

    USP3

    背景

    Background: Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PARK2): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin\\\'s ability to drive mitophagy (PubMed:18287522, PubMed:24896179, PubMed:25527291, PubMed:25621951). Preferentially cleaves \\\'Lys-6\\\'- and \\\'Lys-11\\\'-linked polyubiquitin chains, 2 types of linkage that participate to mitophagic signaling (PubMed:25621951). Does not cleave efficiently polyubiquitin phosphorylated at \\\'Ser-65\\\' (PubMed:25527291). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (By similarity).

    Aliases: Deubiquitinating enzyme 30 antibody, FLJ40511 antibody, Ub-specific protease 30 antibody, Ubiquitin carboxyl terminal hydrolase 30 antibody, Ubiquitin carboxyl-terminal hydrolase 30 antibody, Ubiquitin specific peptidase 30 antibody, Ubiquitin specific processing protease 30 antibody, Ubiquitin thioesterase 30 antibody, Ubiquitin thiolesterase 30 antibody, Ubiquitin-specific-processing protease 30 antibody, UBP30_HUMAN antibody, usp30 antibody

    UniProt

    Q70CQ3
You are here:
Chat with us!