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USP2 抗体 (C-Term) (Biotin)

This anti-USP2 antibody is a 兔 多克隆 antibody detecting USP2 in ELISA. Suitable for 人.
产品编号 ABIN7174285
发货至: 中国

Quick Overview for USP2 抗体 (C-Term) (Biotin) (ABIN7174285)

抗原

See all USP2 抗体
USP2 (Ubiquitin Specific Peptidase 2 (USP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This USP2 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 258-417, C-Term

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 20 protein (258-417AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    USP2 (Ubiquitin Specific Peptidase 2 (USP2))

    别名

    USP2

    背景

    Background: Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains.

    Aliases: Deubiquitinating enzyme 20 antibody, hVDU2 antibody, KIAA1003 antibody, LSFR 3A antibody, LSFR3A antibody, pVHL interacting deubiquitinating enzyme 2 antibody, Ubiquitin carboxyl terminal hydrolase 20 antibody, Ubiquitin carboxyl-terminal hydrolase 20 antibody, ubiquitin specific peptidase 20 antibody, Ubiquitin specific processing protease 20 antibody, Ubiquitin specific protease 20 antibody, Ubiquitin thioesterase 20 antibody, Ubiquitin thiolesterase 20 antibody, Ubiquitin-specific-processing protease 20 antibody, UBP20_HUMAN antibody, USP 20 antibody, USP20 antibody, VDU 2 antibody, VDU2 antibody, VHL interacting deubiquitinating enzyme 2 antibody, VHL-interacting deubiquitinating enzyme 2 antibody

    UniProt

    Q9Y2K6
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