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USP2 抗体 (AA 9-265) (FITC)

This anti-USP2 antibody is a 兔 多克隆 antibody detecting USP2 in . Suitable for 人.
产品编号 ABIN7174282
发货至: 中国

Quick Overview for USP2 抗体 (AA 9-265) (FITC) (ABIN7174282)

抗原

See all USP2 抗体
USP2 (Ubiquitin Specific Peptidase 2 (USP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This USP2 antibody is conjugated to FITC

应用范围

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  • 抗原表位

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    AA 9-265

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 2 protein (9-265AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    USP2 (Ubiquitin Specific Peptidase 2 (USP2))

    别名

    USP2

    背景

    Background: Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4. Plays a role in the G1/S cell-cycle progression in normal and cancer cells. Plays a role in the regulation of myogenic differentiation of embryonic muscle cells. Regulates the circadian clock by modulating its intrinsic circadian rhythm and its capacity to respond to external cues. Associates with clock proteins and deubiquitinates core clock component PER1 but does not affect its overall stability. Regulates the nucleocytoplasmic shuttling and nuclear retention of PER1 and its repressive role on the clock transcription factors CLOCK and ARNTL/BMAL1 (By similarity).

    Aliases: 41 kDa ubiquitin specific protease antibody, 41 kDa ubiquitin-specific protease antibody, Deubiquitinating enzyme 2 antibody, Ubiquitin carboxyl terminal hydrolase 2 antibody, Ubiquitin carboxyl-terminal hydrolase 2 antibody, ubiquitin specific peptidase 2 antibody, Ubiquitin specific processing protease 2 antibody, Ubiquitin specific protease 12 antibody, Ubiquitin specific protease 9 antibody, Ubiquitin specific protease, 41kD antibody, Ubiquitin thioesterase 2 antibody, Ubiquitin thiolesterase 2 antibody, Ubiquitin-specific-processing protease 2 antibody, Ubiquitin-specific-processing protease testis antibody, UBP-t antibody, UBP2_HUMAN antibody, UBP41 antibody, USP2 antibody, USP9 antibody

    UniProt

    O75604
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