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TRIB1 抗体 (AA 3-91)

The 兔 多克隆 anti-TRIB1 antibody is suitable to detect TRIB1 in samples from 人. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN7173357
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TRIB1 抗体 (AA 3-91) (ABIN7173357)

抗原

See all TRIB1 抗体
TRIB1 (Tribbles Homolog 1 (TRIB1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TRIB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 3-91

    原理

    TRIB1 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Tribbles homolog 1 protein (3-91AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TRIB1 (Tribbles Homolog 1 (TRIB1))

    别名

    TRIB1

    背景

    Background: Adapter protein involved in protein degradation by interacting with RFWD2/COP1 ubiquitin ligase (PubMed:27041596). The RFWD2-binding motif is masked by autoinhibitory interactions with the protein kinase domain (PubMed:26455797). Serves to alter RFWD2 substrate specificity by directing the activity of RFWD2 toward CEBPA (PubMed:27041596). Binds selectively the recognition sequence of CEBPA (PubMed:26455797). Regulates myeloid cell differentiation by altering the expression of CEBPA in a RFWD2-dependent manner (By similarity). Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (By similarity). Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity (PubMed:15299019, PubMed:26455797).

    Aliases: C8FW antibody, G-protein-coupled receptor-induced gene 2 protein antibody, GIG-2 antibody, GIG2 antibody, SKIP1 antibody, TRB-1 antibody, TRB1 antibody, Trib1 antibody, TRIB1_HUMAN antibody, Tribbles homolog 1 antibody

    UniProt

    Q96RU8

    途径

    Smooth Muscle Cell Migration
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