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Transferrin Receptor 抗体 (AA 94-754)

TFRC 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7172795
发货至: 中国
  • 抗原 See all Transferrin Receptor (TFRC) 抗体
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    抗原表位
    • 15
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    • 5
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    AA 94-754
    适用
    • 177
    • 84
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    • 4
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    • 2
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    宿主
    • 102
    • 92
    • 28
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    • 1
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    克隆类型
    • 138
    • 83
    • 4
    多克隆
    标记
    • 111
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    This Transferrin Receptor antibody is un-conjugated
    应用范围
    • 136
    • 112
    • 57
    • 57
    • 52
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Transferrin receptor protein 1 protein (94-754AA)
    亚型
    IgG
    Top Product
    Discover our top product TFRC Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    别名
    TFRC (TFRC 产品)
    背景

    Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

    Aliases: CD 71 antibody, CD71 antibody, CD71 antigen antibody, IMD46 antibody, OTTHUMP00000208523 antibody, OTTHUMP00000208524 antibody, OTTHUMP00000208525 antibody, p90 antibody, sTfR antibody, T9 antibody, TFR 1 antibody, TfR antibody, TfR1 antibody, TFR1_HUMAN antibody, TFRC antibody, TR antibody, Transferrin receptor (p90 CD71) antibody, Transferrin receptor protein 1, serum form antibody, Trfr antibody

    UniProt
    P02786
    途径
    Transition Metal Ion Homeostasis
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