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CTCFL 抗体 (AA 1-270)

This anti-CTCFL antibody is a 兔 多克隆 antibody detecting CTCFL in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7172781
发货至: 中国

Quick Overview for CTCFL 抗体 (AA 1-270) (ABIN7172781)

抗原

See all CTCFL 抗体
CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

适用

  • 27
  • 11
  • 2

宿主

  • 31
  • 1
  • 1
  • 1

克隆类型

  • 32
  • 2
多克隆

标记

  • 16
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CTCFL antibody is un-conjugated

应用范围

  • 29
  • 13
  • 13
  • 13
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-270

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Transcriptional repressor CTCFL protein (1-270AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

    别名

    CTCFL

    背景

    Background: Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 \\\'Arg-3\\\' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.

    Aliases: BORIS like protein antibody, Brother of the regulator of imprinted sites antibody, Cancer/testis antigen 27 antibody, CCCTC binding factor (zinc finger protein) like antibody, CCCTC-binding factor antibody, CT27 antibody, CTCF paralog antibody, CTCF T antibody, CTCF-like protein antibody, Ctcfl antibody, CTCFL_HUMAN antibody, dJ579F20.2 antibody, HMG 1L1 antibody, HMGB1L1 antibody, MGC163358 antibody, MGC169105 antibody, MGC169106 antibody, Putative high mobility group protein 1 like 1 antibody, Putative high mobility group protein B1 like 1 antibody, Transcriptional repressor CTCFL antibody, Zinc finger protein CTCF-T antibody

    UniProt

    Q8NI51
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