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TRIM24 抗体 (AA 891-1012)

This anti-TRIM24 antibody is a 兔 多克隆 antibody detecting TRIM24 in ELISA. Suitable for 人.
产品编号 ABIN7172708
发货至: 中国

Quick Overview for TRIM24 抗体 (AA 891-1012) (ABIN7172708)

抗原

See all TRIM24 抗体
TRIM24 (Tripartite Motif Containing 24 (TRIM24))

适用

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宿主

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克隆类型

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多克隆

标记

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This TRIM24 antibody is un-conjugated

应用范围

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ELISA
  • 抗原表位

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    AA 891-1012

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Transcription intermediary factor 1-alpha protein (891-1012AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TRIM24 (Tripartite Motif Containing 24 (TRIM24))

    别名

    TRIM24

    背景

    Background: Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at \\\'Lys-4\\\' (H3K4me0) and acetylated at \\\'Lys-23\\\' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes (By similarity).

    Aliases: E3 ubiquitin protein ligase TRIM24 antibody, E3 ubiquitin-protein ligase Trim24 antibody, hTIF1 antibody, PTC6 antibody, RING finger protein 82 antibody, RNF82 antibody, TF1A antibody, TIF1 alpha antibody, TIF1 antibody, TIF1-alpha antibody, TIF1A antibody, TIF1A_HUMAN antibody, TIF1ALPHA antibody, Transcription intermediary factor 1-alpha antibody, Transcriptional intermediary factor 1 alpha antibody, Transcriptional intermediary factor 1 antibody, Trim24 antibody, Tripartite motif containing 24 antibody, Tripartite motif-containing protein 24 antibody

    UniProt

    O15164
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