E2F6 抗体 (AA 1-281)
Quick Overview for E2F6 抗体 (AA 1-281) (ABIN7172529)
抗原
See all E2F6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-281
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Transcription factor E2F6 protein (1-281AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- E2F6 (E2F Transcription Factor 6 (E2F6))
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别名
- E2F6
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背景
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Background: Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5\\\'-TTTC[CG]CGC-3\\\'. Has a preference for the 5\\\'-TTTCCCGC-3\\\' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.
Aliases: E2F 6 antibody, E2F binding site modulating activity protein antibody, E2F transcription factor 6 antibody, E2F transcription factor 6 isoform 1 antibody, E2F-6 antibody, E2F6 antibody, E2F6_HUMAN antibody, EMA antibody, MGC111545 antibody, Transcription factor E2F6 antibody
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UniProt
- O75461
抗原
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