TRIAP1 抗体 (AA 1-76)
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北京 101111
Quick Overview for TRIAP1 抗体 (AA 1-76) (ABIN7172318)
抗原
See all TRIAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-76
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原理
- TRIAP1 Antibody
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human TP53-regulated inhibitor of apoptosis 1 protein (1-76AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))
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别名
- TRIAP1
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背景
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Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003).
Aliases: p53-inducible cell-survival factor antibody, p53CSV antibody, Protein 15E1.1 antibody, TP53-regulated inhibitor of apoptosis 1 antibody, TRIA1_HUMAN antibody, Triap1 antibody, WF 1 antibody, WF1 antibody
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UniProt
- O43715
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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