THO Complex 4 抗体 (AA 186-240) (Biotin)
Quick Overview for THO Complex 4 抗体 (AA 186-240) (Biotin) (ABIN7172056)
抗原
See all THO Complex 4 (THOC4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 186-240
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human THO complex subunit 4 protein (186-240AA)
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亚型
- IgG
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anti-THO Complex 4 (THOC4) antibody
THOC4 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 4 (THOC4) antibodyTHOC4 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 4 (THOC4) (AA 106-193) antibodyTHOC4 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-THO Complex 4 (THOC4) antibodyTHOC4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-THO Complex 4 (THOC4) (AA 186-240) antibodyTHOC4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 4 (THOC4) antibodyTHOC4 适用: 人, 非洲爪蟾 WB, ELISA, IF, IP, IHC (p), ICC, FACS, ChIP, EM 宿主: 小鼠 Monoclonal 11G5 unconjugated
anti-THO Complex 4 (THOC4) antibodyTHOC4 适用: 人, 小鼠, 非洲爪蟾 WB, ELISA, IF, IP, IHC (p), ICC, FACS, ChIP, EM 宿主: 小鼠 Monoclonal 11G5 unconjugated
anti-THO Complex 4 (THOC4) (Internal Region) antibodyTHOC4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 4 (THOC4) (AA 58-107) antibodyTHOC4 适用: 人, 小鼠, 大鼠, 非洲爪蟾, Cow, 斑马鱼, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 4 (THOC4) (N-Term) antibodyTHOC4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- THO Complex 4 (THOC4)
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别名
- ALYREF
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背景
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Background: Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\\\' end of the mRNA where it functions in mRNA export to the cytoplasm. TREX recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi\\\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production, ALYREF/THOC4 mediates the recruitment of the TREX complex to the intronless viral mRNA. Required for TREX complex assembly and for linking DDX39B to the cap-binding complex (CBC). In conjunction with THOC5 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA, both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in the nuclear export of intronless mRNA, proposed to be recruited to intronless mRNA by ATP-bound DDX39B. Involved in transcription elongation and genome stability.
Aliases: Ally of AML-1 and LEF-1 antibody, Ally of AML1 and LEF1 antibody, ALY antibody, ALY/REF antibody, Aly/REF export factor antibody, BEF antibody, bZIP enhancing factor antibody, bZIP-enhancing factor BEF antibody, REF antibody, THO complex 4 antibody, THO complex subunit 4 antibody, Tho4 antibody, thoc4 antibody, THOC4_HUMAN antibody, Transcriptional coactivator Aly/REF antibody, Transcriptional coactivator antibody
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UniProt
- Q86V81
抗原
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