THO Complex 3 抗体 (AA 2-351)
Quick Overview for THO Complex 3 抗体 (AA 2-351) (ABIN7172051)
抗原
See all THO Complex 3 (THOC3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-351
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human THO complex subunit 3 protein (2-351AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- THO Complex 3 (THOC3)
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别名
- THOC3
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背景
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Background: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
Aliases: hTREX45 antibody, TEX1 homolog antibody, THO complex subunit 3 antibody, Tho3 antibody, THOC3 antibody, THOC3_HUMAN antibody
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UniProt
- Q96J01
抗原
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