TPMT 抗体 (AA 4-244) (Biotin)
Quick Overview for TPMT 抗体 (AA 4-244) (Biotin) (ABIN7171993)
抗原
See all TPMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-244
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Thiopurine S-methyltransferase protein (4-244AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TPMT (Thiopurine S-Methyltransferase (TPMT))
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别名
- TPMT
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背景
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Background: TPMT is an enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Aliases: HGNC:12014 antibody, S adenosyl L methionine thiopurine S methyltransferase antibody, Thiopurine methyltransferase antibody, Thiopurine S methyltransferase antibody, Thiopurine S-methyltransferase antibody, TPMT antibody, TPMT_HUMAN antibody
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UniProt
- P51580
抗原
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