TSPAN12 抗体 (AA 111-224)
Quick Overview for TSPAN12 抗体 (AA 111-224) (ABIN7171846)
抗原
See all TSPAN12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 111-224
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Tetraspanin-12 protein (111-224AA)
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亚型
- IgG
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anti-Tetraspanin 12 (TSPAN12) (AA 111-224) antibody
TSPAN12 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) antibodyTSPAN12 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 185-234) antibodyTSPAN12 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, 猴, Pig WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 232-259), (C-Term) antibodyTSPAN12 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22652 unconjugated
anti-Tetraspanin 12 (TSPAN12) antibodyTSPAN12 适用: 人 WB, FACS, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 1-100) antibodyTSPAN12 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 179-228) antibodyTSPAN12 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (Middle Region) antibodyTSPAN12 适用: 人, 大鼠, 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TSPAN12 (Tetraspanin 12 (TSPAN12))
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别名
- TSPAN12
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背景
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Background: Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity). Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP). Activates MMP14/MT1-MMP-dependent cleavage activity.
Aliases: TSPAN12 antibody, NET2 antibody, TM4SF12 antibody, UNQ774/PRO1568Tetraspanin-12 antibody, Tspan-12 antibody, Tetraspan NET-2 antibody, Transmembrane 4 superfamily member 12 antibody
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UniProt
- O95859
抗原
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