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Tenascin R 抗体 (AA 1231-1319) (HRP)

This anti-Tenascin R antibody is a 兔 多克隆 antibody detecting Tenascin R in ELISA. Suitable for 人.
产品编号 ABIN7171753
发货至: 中国

Quick Overview for Tenascin R 抗体 (AA 1231-1319) (HRP) (ABIN7171753)

抗原

See all Tenascin R (TNR) 抗体
Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

适用

  • 38
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宿主

  • 37
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克隆类型

  • 40
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多克隆

标记

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This Tenascin R antibody is conjugated to HRP

应用范围

  • 13
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ELISA
  • 抗原表位

    • 15
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    AA 1231-1319

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Tenascin-R protein (1231-1319AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

    别名

    TNR

    背景

    Background: Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance (By similarity).

    Aliases: Janusin antibody, MGC149328 antibody, Restrictin antibody, Tenascin R (restrictin, janusin) antibody, Tenascin-R antibody, TENR_HUMAN antibody, TN-R antibody, Tnr antibody

    UniProt

    Q92752

    途径

    Regulation of Cell Size
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