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TERT 抗体 (AA 281-436)

This anti-TERT antibody is a 兔 多克隆 antibody detecting TERT in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7171713
发货至: 中国

Quick Overview for TERT 抗体 (AA 281-436) (ABIN7171713)

抗原

See all TERT 抗体
TERT (Telomerase Reverse Transcriptase (TERT))

适用

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宿主

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克隆类型

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多克隆

标记

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This TERT antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 281-436

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Telomerase reverse transcriptase protein (281-436AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TERT (Telomerase Reverse Transcriptase (TERT))

    别名

    TERT

    背景

    Background: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.

    Aliases: CMM9 antibody, DKCA2 antibody, DKCB4 antibody, EST2 antibody, HEST2 antibody, htert antibody, hTRT antibody, PFBMFT1 antibody, TCS1 antibody, Telomerase associated protein 2 antibody, Telomerase catalytic subunit antibody, Telomerase reverse transcriptase antibody, Telomerase-associated protein 2 antibody, Telomere Reverse Transcriptase antibody, TERT antibody, TERT_HUMAN antibody, TP2 antibody, TRT antibody

    UniProt

    O14746

    途径

    Telomere Maintenance
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