SDCBP 抗体 (AA 21-228) (Biotin)
Quick Overview for SDCBP 抗体 (AA 21-228) (Biotin) (ABIN7171274)
抗原
See all SDCBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-228
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Syntenin-1 protein (21-228AA)
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亚型
- IgG
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anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-100) antibody
SDCBP 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-298) antibodySDCBP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 21-228) antibodySDCBP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-298) antibodySDCBP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) antibodySDCBP 适用: 人, 大鼠, 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (Internal Region) antibodySDCBP 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) antibodySDCBP 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-30), (N-Term) antibodySDCBP 适用: 人 WB 宿主: 兔 Polyclonal RB42325 unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 101-150) antibodySDCBP 适用: 人, 大鼠, 小鼠, 犬, Pig, Cow, 马, 豚鼠, 兔, 小鸡, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-260) antibodySDCBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
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别名
- SDCBP
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背景
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Background: Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis (PubMed:26291527). Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1 (PubMed:25893292). In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis (PubMed:22660413). Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer types (PubMed:26539120). In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) (PubMed:11498591). May also play a role in vesicular trafficking (PubMed:11179419). Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (PubMed:10230395).
Aliases: MDA-9 antibody, MDA9 antibody, Melanoma differentiation-associated protein 9 antibody, Pro-TGF-alpha cytoplasmic domain-interacting protein 18 antibody, Scaffold protein Pbp1 antibody, SDCB1_HUMAN antibody, SDCBP antibody, ST1 antibody, SYCL antibody, Syndecan binding protein (syntenin) antibody, Syndecan binding protein 1 antibody, Syndecan-binding protein 1 antibody, Syntenin 1 antibody, Syntenin-1 antibody, TACIP18 antibody
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UniProt
- O00560
抗原
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