SMC6 抗体 (AA 309-450) (Biotin)
Quick Overview for SMC6 抗体 (AA 309-450) (Biotin) (ABIN7170875)
抗原
See all SMC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 309-450
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Structural maintenance of chromosomes protein 6 protein (309-450AA)
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亚型
- IgG
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anti-SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6) (AA 1-110) antibody
SMC6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6) (AA 309-450) antibodySMC6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))
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别名
- SMC6
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背景
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Background: Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome (PubMed:26983541).
Aliases: FLJ22116 antibody, FLJ35534 antibody, hSMC6 antibody, SMC 6 antibody, SMC protein 6 antibody, SMC-6 antibody, SMC6 antibody, SMC6 protein antibody, SMC6 structural maintenance of chromosomes 6 like 1 antibody, SMC6_HUMAN antibody, Smc6l1 antibody, Structural maintenance of chromosomes 6 antibody, Structural maintenance of chromosomes 6 like 1 antibody, Structural maintenance of chromosomes protein 6 antibody
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UniProt
- Q96SB8
抗原
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