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STIM1 抗体 (AA 2-350)

STIM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7170833
发货至: 中国
  • 抗原 See all STIM1 抗体
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    抗原表位
    • 15
    • 15
    • 15
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-350
    适用
    • 71
    • 55
    • 25
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 76
    • 8
    • 1
    • 1
    克隆类型
    • 70
    • 16
    多克隆
    标记
    • 38
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This STIM1 antibody is un-conjugated
    应用范围
    • 43
    • 30
    • 26
    • 26
    • 24
    • 19
    • 10
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Stromal interaction molecule 1 protein (2-350AA)
    亚型
    IgG
    Top Product
    Discover our top product STIM1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    别名
    STIM1 (STIM1 产品)
    别名
    stim1 antibody, MGC76045 antibody, STIM1 antibody, si:dkey-24p1.5 antibody, MGC154748 antibody, si:ch211-112l17.2 antibody, Stim1 antibody, D11S4896E antibody, GOK antibody, TAM antibody, SIM antibody, stromal interaction molecule 1 antibody, stromal interaction molecule 1a antibody, stromal interaction molecule 1 L homeolog antibody, stromal interaction molecule 1b antibody, STIM1 antibody, stim1 antibody, stim1a antibody, stim1.L antibody, stim1b antibody, Stim1 antibody
    背景

    Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:15866891, PubMed:16005298, PubMed:16208375, PubMed:16537481, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:18854159, PubMed:19249086, PubMed:22464749, PubMed:24069340, PubMed:24351972, PubMed:24591628, PubMed:26322679, PubMed:25326555). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375, PubMed:16537481). Involved in enamel formation (PubMed:24621671). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (PubMed:26322679).

    Aliases: D11S4896E antibody, GOK antibody, OTTHUMP00000164512 antibody, OTTHUMP00000229140 antibody, OTTHUMP00000230742 antibody, SIM antibody, STIM 1 antibody, STIM1 antibody, Stim1 stromal interaction molecule 1 antibody, STIM1_HUMAN antibody, STIM1L antibody, Stromal interaction molecule 1 antibody

    UniProt
    Q13586
    途径
    TCR Signaling, BCR Signaling
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